Farrellys Baste a New Comedy

Peter and Bobby Farrelly are on a roll lately. They are currently filming The Heartbreak Kid with Ben Stiller, may or may not tackle the latest Three Stooges project and have just announced a new comedy based on a Jeffrey Euginedes short story called Baster, which they will write, direct, and executive produce. They describe it as a "character driven comedy for the in vitro age," so it doesn't take too much of a leap of faith to figure out the subject matter (batter?) of this film.

Casting has not yet been announced for the new flick, but we imagine a madcap, zany comedy where the lead character tries to find a sperm donor so she can be a mommy. For some reason I keep picturing Joan Cusack, because she's great at madcap, zany and slapstick, but it'll probably be someone younger. Especially since they'll need to emphasize the sex (or lack thereof?) in this movie. Plus the entire process of in vitro fertilization will probably get an enormous amount of attention from the Farrellys, who are huge fans of gross-out humor.

Who would you like to see in this role? Do you have a favorite female comedian who can handle Peter and Bobby?